You are in Herbal Remedies for Women's Health > Xiao Jin Wan
Detailed Specification
0.6g x 4 bottle box
£10.95
Xiao Jin Wan
Manufacturer : Chengdu Yongkang Pharmaceutical
Packing : 0.6g x 4 bottle box
Pharmaceutical Ingredients : Chinese Herbal
Product Category : Women's Health
Code KS0404
4 box course
£32.95
Code KS4404
Pinyin name : Xiao Jin Wan.
Functions and Indications : For various types of diseases including cancers, such as breast cancer. To remove blood stasis, promote blood circulation and alleviating pain.
About Xiao Jin Wan : A traditional Chinese herbal formula, inhibits proliferation via arresting cell cycle progression at the G2/M phase and promoting apoptosis via activating the mitochondrial-dependent pathway in U-2OS human osteosarcoma cells.
Xiao Jin Wan (XJW) is a well-known traditional Chinese folk-medicine, which is commonly used for the treatment of various types of diseases including cancers. However, the mechanism of the anticancer activity of XJW against U-2OS human osteosarcoma cells, have not yet been reported. In the present study, we investigated the cellular effects of the XJW on the U-2OS human osteosarcoma cell line. Our results showed that XJW induced cell morphological changes, reduced cell viability in a dose- and time-dependent manner and arrested in the G2/M phase of the cell cycle suggesting that XJW inhibited the proliferation of U-2OS cells. Hoechst 33258 staining and Annexin V/propidium iodide double staining exhibited the typical nuclear features of apoptosis and increased the proportion of apoptotic Annexin V-positive cells in a dose-dependent manner, respectively. In addition, XJW treatment caused loss of plasma membrane asymmetry, collapse of mitochondrial membrane potential, activation of caspase-9 and caspase-3, and increase of the ratio of pro-apoptotic Bax to anti-apoptotic Bcl-2. Taken together, the results indicate that the U-2OS cell growth inhibitory activity of XJW was due to cell cycle arrested and mitochondrial-mediated apoptosis, which may partly explain the anticancer activity of Xiao Jin Wan.
Main Ingredients : Synthetic Musk, Cochinchina Momordica Seed,Kusnezoff Monkshood Root (Prepared),Beautiful Sweetgum Resin Resina Liquidambaris,Frankincense Olibanum,Myrrh Myrrha,Trogopterus,Chinese Angelica Root,Earthworm Pheretima.
Character : This product is dark brown pellets, bitter tast.
Usage and Dosage : Oral, take 2g, twice a day. Children half dosage.
Packaging Specifications: 0.6g × 4 bottle box .
Inappropriate : Pregnant women should not use.
Storage : Keep sealed.
Functions and Indications : For various types of diseases including cancers, such as breast cancer. To remove blood stasis, promote blood circulation and alleviating pain.
About Xiao Jin Wan : A traditional Chinese herbal formula, inhibits proliferation via arresting cell cycle progression at the G2/M phase and promoting apoptosis via activating the mitochondrial-dependent pathway in U-2OS human osteosarcoma cells.
Xiao Jin Wan (XJW) is a well-known traditional Chinese folk-medicine, which is commonly used for the treatment of various types of diseases including cancers. However, the mechanism of the anticancer activity of XJW against U-2OS human osteosarcoma cells, have not yet been reported. In the present study, we investigated the cellular effects of the XJW on the U-2OS human osteosarcoma cell line. Our results showed that XJW induced cell morphological changes, reduced cell viability in a dose- and time-dependent manner and arrested in the G2/M phase of the cell cycle suggesting that XJW inhibited the proliferation of U-2OS cells. Hoechst 33258 staining and Annexin V/propidium iodide double staining exhibited the typical nuclear features of apoptosis and increased the proportion of apoptotic Annexin V-positive cells in a dose-dependent manner, respectively. In addition, XJW treatment caused loss of plasma membrane asymmetry, collapse of mitochondrial membrane potential, activation of caspase-9 and caspase-3, and increase of the ratio of pro-apoptotic Bax to anti-apoptotic Bcl-2. Taken together, the results indicate that the U-2OS cell growth inhibitory activity of XJW was due to cell cycle arrested and mitochondrial-mediated apoptosis, which may partly explain the anticancer activity of Xiao Jin Wan.
Main Ingredients : Synthetic Musk, Cochinchina Momordica Seed,Kusnezoff Monkshood Root (Prepared),Beautiful Sweetgum Resin Resina Liquidambaris,Frankincense Olibanum,Myrrh Myrrha,Trogopterus,Chinese Angelica Root,Earthworm Pheretima.
Character : This product is dark brown pellets, bitter tast.
Usage and Dosage : Oral, take 2g, twice a day. Children half dosage.
Packaging Specifications: 0.6g × 4 bottle box .
Inappropriate : Pregnant women should not use.
Storage : Keep sealed.
Menu of Categories
Chinese Herbal Medicine
Website www.china-herbal.co.uk - Email mail@china-herbal.co.uk
Copyright (C) 2010 - 2020 Global Health Foods. All rights reserved
Chinese Medicine, Herbal Medicine, Chinese Herbal Medicine
Chinese Medicine
Chinese Herbal Medicine
Chinese Medicine Pharmacy
Traditional Chinese Medicine
Leading Brand Chinese Herbal Medicine
Chinese Tea
Natural Health Supplements
Herbal Remedies
Natural Cures
Since 2009
